Association between weight gain during adjuvant chemotherapy for early-stage breast cancer and survival outcomes

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Association between weight gain during adjuvant chemotherapy for early‐stage breast cancer and survival outcomes

Obese and overweight women have an increased risk of breast cancer and worse outcomes at the time of diagnosis. Women tend to gain weight after breast cancer diagnosis and during chemotherapy for early-stage disease, which may in turn increase risk for worse outcomes. We examined if weight gained during adjuvant chemotherapy was associated with worse survival outcomes. We queried our database f...

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[Adjuvant chemotherapy of early stage breast cancer].

UNLABELLED Adjuvant systemic therapy reduces the likelihood of both local and distant relapses by eradicating micrometastases. AIM To survey the adjuvant treatment of early breast cancer. METHODS Author presents an overview of the systemic therapy of early breast cancer based on relevant literature and own experiences. RESULTS Three systemic treatment modalities are widely used as adjuvan...

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The impact of weight gain during adjuvant chemotherapy on survival in breast cancer.

OBJECTIVE Weight gain can be detected during adjuvant chemotherapy in breast cancer patients, leading to administration of lower drug doses than planned and a decrease in long-term survival. In this study, the effect of weight gain on survival in breast cancer patients was investigated. MATERIAL AND METHODS Breast cancer patients treated with adjuvant chemotherapy between May 2002 and May 200...

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Stage II breast cancer: differences between four coping patterns in side effects during adjuvant chemotherapy.

Fifty-six women with stage II breast cancer receiving adjuvant chemotherapy were recruited for a study evaluating and comparing coping patterns for differences in physical and psychological side effects during treatment with adjuvant chemotherapy. Cluster analyses were used to split women into confrontive, avoidant-confrontive, avoidant-resigned, and resigned coping clusters. Side-effect measur...

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Weight changes during chemotherapy for breast cancer.

CONTEXT Patients receiving adjuvant chemotherapy for breast cancer have a tendency to gain weight. This tendency has determining factors not completely defined and an unknown prognostic impact. OBJECTIVE To evaluate weight change during chemotherapy for breast cancer in a defined population and to identify its predisposing factors and possible prognostic significance. DESIGN Observational, ...

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ژورنال

عنوان ژورنال: Cancer Medicine

سال: 2017

ISSN: 2045-7634

DOI: 10.1002/cam4.1207